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Tuesday 27 June |
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11.00 - 12.15 |
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Registration |
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12.15 - 13.00 |
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Lunch |
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13.00 - 13.15 |
Session 1 |
Course aims (Gordon Dear) |
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13.15 - 14.00 |
Session 2 |
The physicochemical properties of drugs: part I (Angus Nedderman) |
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14.00 - 14.50 |
Session 3 |
Opening tutorial (ice breaker) |
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14.50 - 15.30 |
Session 4 |
The physicochemical properties of drugs: part II (Angus Nedderman) |
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15.30 - 15.45 |
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Tea break |
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15.45 - 16.30 |
Session 5 |
Fundamentals of mass spectrometry (MS): part I (Dave Berry) |
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16.30 - 17.00 |
Session 6 |
Retention mechanisms (John Allanson) |
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17.00 - 17.45 |
Session 7 |
Fundamentals of mass spectrometry (MS): part II (Benno Ingelse)
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19.00 |
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Evening meal and mixer
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Wednesday 28 June |
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09.00 - 09.30 |
Session 8 |
Fundamentals of Liquid Chromatography (LC): part I (John Allanson) |
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09.30 - 10.15 |
Session 9 |
Tutorial on basic HPLC |
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10.15 - 11.00 |
Session 10 |
Fundamentals of Liquid Chromatography (LC): part II (John Allanson) |
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11.00 - 11.15 |
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Coffee break |
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11.15 - 12.15 |
Session 11 |
Quantitative mass spectrometry (MS) (Dave Berry) |
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12.15 - 13.15 |
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Lunch |
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13.15 - 14.15 |
Session 12 |
Sample preparation (John Allanson) |
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14.15 - 15.15 |
Session 13 |
Tutorial on quantitative mass spectrometry (MS) |
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15.15 - 15.30 |
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Tea break |
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15.30 - 16.00 |
Session 14 |
Alternative Liquid Chromatography (LC) approaches (Mohammed Abrar) |
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16.00 - 17.00 |
Session 15 |
Tutorial on Sample Preparation
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19.00 |
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Evening meal
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Thursday 29 June |
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09.00 - 09.30 |
Session 16 |
Introduction to metabolite identification (Angus Nedderman) |
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09.30 - 10.30 |
Session 17 |
Metabolite identification: part I (Gordon Dear) |
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10.30 - 10.45 |
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Coffee break |
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10.45 - 11.45 |
Session 18 |
Metabolite identification: part II (Gordon Dear) |
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11.45 - 12.30 |
Session 19 |
Tutorial on metabolite identification |
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12.30 - 13.30 |
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Lunch |
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13.30 - 14.00 |
Session 20 |
Optimising Liquid Chromatography (LC) methods (Mohammed Abrar) |
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14.00 - 14.45 |
Session 21 |
Biopharmaceutical analysis: part I – LC/MS of intact peptides and oligonucleotides
(Mohammed Abrar) |
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14.45 - 15.00 |
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Tea break |
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15.00 - 16.00 |
Session 22 |
Biopharmaceutical analysis: part II – Large biomolecule analysis using signature peptides (LC/MS) and comparison with ligand
binding (Benno Ingelse) |
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16.00 - 17.00 |
Session 23 |
Tutorial on biopharmaceutical analysis |
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17.00 - 17.45 |
Session 24 |
Metabolite identification strategies (Gordon Dear)
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19.00 |
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Course dinner
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Friday 30 June |
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09.00 - 10.00 |
Session 25 |
Strategies for method development: part I (Mohammed Abrar) |
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10.00 - 10.15 |
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Coffee break |
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10.15 - 11.15 |
Session 26 |
Strategies for method development: part II and Q&A (Mohammed Abrar, John Allanson, Dave Berry) |
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11.15 - 12.00 |
Session 27 |
Tutorial on LC/MS pitfalls & method development |
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12.00 - 12.15 |
Session 28 |
Closing remarks (Gordon Dear) |
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