The DMDG organises training courses and scientific meetings for the benefit
of its membership. Here is further information on the DMDG courses and meetings.
Membership of the DMDG is FREE and by company site, although
individuals who work at a member site can sign up to receive information
about individual DMDG
meetings and training courses. Applications for membership are considered by
Management Committee that conducts the business of the
|Large Molecules Course
The 'large molecules' to be discussed in the course include oligonucleotides,
antibodies, antibody fragments and proteins. The following topics will be discussed:
ADME and PK/PD
|Fundamentals of DMPK Course
This course is intended for new DMPK scientists, or those from other scientific
disciplines, who would like a broad introduction to DMPK science. This course
covers a range of topics highlighting the pivotal role played by DMPK throughout
the drug discovery and development process. Specific consideration is given to
topics as diverse as, in vitro metabolism, pharmacokinetics, quantitative analytical
techniques, qualitative detection methodology and isotopic techniques. In addition,
consideration is also given to topics which have taken on a greater prevalence
in recent years, for example, modelling & simulation techniques and an introduction
to the DMPK aspects of large molecules.
|Pharmacokinetics in Drug Discovery course
The objectives for the DMDG course on Pharmacokinetics in Drug Discovery are to develop an understanding and
appreciation of the importance and contribution of drug metabolism and pharmacokinetics to drug design by first
intent. The course highlights the importance of physicochemical properties in drug design and covers the fundamental
aspects of pharmacokinetics and pharmacodynamics, safety study design and toxicokinetics, the importance of ADME and the relevance of metabolite pharmacokinetics.
It is recommended that this course is taken before attending the 'Introduction to Pharmacokinetic-Pharmacodynamic and Concepts course'.
|Introduction to Pharmacokinetic-Pharmacodynamic and Concepts
Increasingly, DMPK departments are involved in the design and analysis of in vivo
pharmacology (PKPD) experiments. This 2 day course aims to cover the basic concepts
of PKPD that will allow scientists to start practising PKPD interpretation. The
course is for DMPK scientists, and their biology and pharmacology colleagues, who
want to learn more about the PKPD and its uses for drug discovery and development.
It is recommended that the 'Pharmacokinetics in Drug Discovery course' is taken before attending this course.
|In vitro Technology Training Course
This 3 day course should appeal to those scientists just starting their careers in
this area or those from other scientific disciplines who want to learn more of these
approaches and how to apply them to the drug discovery and development process. Topics
to be covered include the enzymology of drug metabolism, enzyme kinetics, induction of
ADME targets, drug transport processes, the use of hepatocytes, slices and subcellular
fractions and the influence of molecular technologies on our discipline.
|Methods for Bioanalysis and Drug Metabolism Course
The agenda includes a series of interactive tutorials interspersed between more formal
lectures, designed to give delegates a deeper understanding of bioanalytical tools employed
within the DMPK environment. The tutorials aim to reinforce lecture material, but in a more
practical form. Topics include:
Physico-chemical Properties of Drugs
Fundamental Aspects of Mass Spectrometry (MS)
|Tissue Distribution Course
This course has been designed to give delegates a broad understanding of whole body autoradiography, from
experimental design through to interpretation of results, including regulatory requirements, human dosimetry
calculations, methodology and instrumentation. Tissue distribution using MSI will also be discussed. The course
is a two day, lecture-based programme, aimed at providing a solid background in autoradiography techniques to
study monitors/managers/directors and technicians wishing to improve their understanding of the theoretical
background. There is also the option to add a practical third day
(at additional cost).
Joint and one day meetings
Meetings held with European partner organisations, such as GMP (France) and SPS (Sweden)
One-day single topic meetings
For more details on
future events, please